Recently I've been reflecting on Dr. Robert Sapolsky’s views on free will. A subject he as described in his book "Determined: A Science of Life without Free Will" where he argues that free will is an illusion, positing that our choices and behaviours are entirely determined by biological and environmental factors beyond our control. I can follow his reasoning but then I got to wonder about how where the placebo effect would fit in his theory. This can seem paradoxical at first glance, but seems they can be reconciled.

It was my believe that the placebo effect typically involved some level of expectation or belief influencing physiological outcomes, which might initially seem to require an act of free will. But if free will is an illusion, as Dr Sapolsky argues, then understanding how a placebo effect can still occur under determinism becomes an interesting puzzle... well I thought so anyway 😅

Understanding the Paradox
Mind as a Product of the Body:

• Sapolsky’s Perspective: Sapolsky argues that what we perceive as “mind” and “free will” are deeply rooted in the biological processes of the brain. Our decisions and behaviours are influenced by a complex interplay of genetics, neurobiology, and environmental factors.
  
• Implication: This means that our thoughts, beliefs, and expectations—key components of the placebo effect—are shaped by underlying biological mechanisms.
  

Placebo Effect:

• Mechanisms: The placebo effect occurs when an individual experiences a real improvement in their condition after receiving a treatment with no therapeutic value. This improvement is due to the individual’s belief in the efficacy of the treatment.
  
• Biological Basis: Research shows that the placebo effect can activate specific neural pathways in the brain that release neurotransmitters like endorphins and dopamine, which can alleviate symptoms and improve health.
  

Reconciling the Two Concepts
Belief and Expectation as Biological Phenomena:

• No Contradiction: If our beliefs and expectations are products of our brain’s biology, then the placebo effect fits within Sapolsky’s framework. The mind’s ability to influence the body through beliefs and expectations does not contradict the idea that these mental states are biologically determined.
  
• Neural Processes: The belief in the effectiveness of a placebo triggers biological processes in the brain that can result in physical changes, such as pain relief or reduced anxiety.
  

Automatic and Unconscious Processes:

• Non-Conscious Influence: Much of what drives the placebo effect happens automatically and unconsciously. The brain’s response to a placebo is not a matter of conscious choice but rather an automatic response to perceived cues.
  
• Learned Associations: The effectiveness of placebos can be partly explained by learned associations. For instance, if taking a pill has historically been associated with feeling better, the brain may automatically initiate healing processes when a placebo pill is taken, based on prior experience.
  

This is a work in progress based on my own thoughts and those of Professor R. Sapolsky’s books, including his latest, “Determined”, as well as A. Damasio’s “The Strange Order of Things” and elements of evolutionary and developmental mismatch theories.

The purpose of this simplified diagram is to gain a better understanding of whether and how we can evolve on purpose to better adapt and manage change. It illustrates the continuous body-mind loop where our body’s neuronal and molecular mechanisms, influenced by genetics, environmental factors, and individual experiences, govern our behaviour. Behavioural changes affect cognition, which in turn shapes the mind. The mind’s decisions, choices, and actions then alter the environment, creating new experiences that continue to influence our body’s mechanisms. Throughout this process, feelings are generated and play a crucial role at each stage.

At the moment, our rising “ biological footprint ” — a term I coined to capture the impact of our lifestyle, environment, and actions on our biological systems — is making us sick.
By understanding the interconnected elements of my illustration, I hope you/we can better comprehend what is happening and why, but also gain insights into how you/we can purposefully change or stimulate a process of evolving on purpose (evolopsis).

How do you feel about this? For example, by reading this, your body has created neuronal and molecular changes that alter your behaviour, perspective, emotions, choices, decisions, and actions, which in turn cause changes in your environment, creating experiences that further influence your body, changing the way you respond, and so on.

What I’m striving for with this illustration is to shed light on my understanding of how you/we can foster better ways of adapting and managing change. In other words, how we can create stability through change and evolve with the changing times, thereby improving our physical and mental health and wellbeing and foster a more compassionate and humane society.
Again it is a work in process… and I’m awaiting Prof. Sapolsky’s view on this.

PS: The key message of Robert Sapolsky’s book Determined: A Science of Life Without Free Will is that human behaviour and decision-making are entirely shaped by a complex interplay of genetics, environmental influences, and individual experiences. Sapolsky argues that the concept of free will is an illusion, and our actions result from deterministic processes involving the body’s neuronal and molecular mechanisms, which influence behaviour and cognition.